Quantification of allospecific and nonspecific corneal endothelial cell damage after corneal transplantation
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چکیده
منابع مشابه
Heterologous corneal endothelial cell transplantation--human corneal endothelial cell transplantation in Lewis rats.
A heterologous corneal endothelial transplantation was attempted using human endothelial cells and a Lewis rat penetrating keratoplasty model. Cultured human endothelial cells were seeded to a Lewis rat cornea, which was denuded of its endothelium. When grafted into the syngeneic Lewis rat, the graft remained clear for at least five days, and then became opaque and edematous because of immune r...
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purpose: to evaluate endothelial cell density (ecd) and morphology of clear corneal grafts after descemet stripping automated endothelial keratoplasty (dsaek) and to determine the factors that influence graft ecd postoperatively. methods: seventy-seven eyes (38 right eyes) of 64 patients (34 female subjects) who underwent dsaek for fuchs’ endothelial dystrophy (n=38) or pseudophakic bullous ker...
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OBJECTIVE To determine whether endothelial cell loss 5 years after successful corneal transplantation is related to the age of the donor. DESIGN Multicenter, prospective, double-masked clinical trial. PARTICIPANTS Three hundred forty-seven subjects participating in the Cornea Donor Study who had not experienced graft failure 5 years after corneal transplantation for a moderate-risk conditio...
متن کاملPrediction of Corneal Condition After Corneal Ring Implantation in Keratoconus Patients
Background: Keratoconus is a common complication among corneal defects. As a result of expeditious and extensive progress of medical science in recent decades, corneal ring implantation has turned into a successful surgical procedure to correct the vision of Keratoconus patients; however, selecting the right patient is essential in the success of the operation. The prediction of corneal conditi...
متن کاملExtended incubation times improve corneal endothelial cell transplantation success.
To investigate the ability of extended incubation times to improve the success of endothelial cell transplantation, eight human donor corneas were denuded of their native endothelium, seeded twice during a 1-hr interval with a suspension of cultured infant human corneal endothelial cells, and then incubated for 144 hr under standard conditions. Subsequently the corneas were transplanted into Af...
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ژورنال
عنوان ژورنال: Eye
سال: 2014
ISSN: 0950-222X,1476-5454
DOI: 10.1038/eye.2014.248